CASE DISCUSSION
Clinical Approach : Megaloblastic anemia in Children
Presented from India by Dr. Bharat Parmar0
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Case Description
Megaloblastic anemia in children is characterized by abnormally large red blood cells (megaloblasts) and is primarily caused by deficiencies in vitamin B12 or folate. A clinical approach to megaloblastic anemia in children begins with a thorough medical history and physical examination to identify...
Case Summary
- Megaloblastic anemia is characterized by large red blood cells (macro-ovalocytes) in peripheral blood smears with immature erythroid cells, and megaloblasts in the bone marrow. It arises from asynchronous maturation of the nucleus and cytoplasm in blood cell precursors due to impaired DNA synthesis. While often caused by vitamin B12 or folate deficiency, rare causes include thymidine deficiency, inborn errors of metabolism, or drug-induced issues.
Speaker Profile
Dr. Bharat Parmar
Professor And Head of Pediatrics at Zydus Medical College, Civil HospitalDr. Bharat Parmar is a distinguished pediatrician serving as Professor and Head of the Department of Pediatrics at Zydus Medical College, Civil Hospital. He has extensive experience in child health, neonatal care, and the management of pediatric diseases. Dr. Parmar is dedicated to advancing pediatric education and clinical excellence through his leadership and academic contributions. His compassionate approach and commitment to medical teaching have made him a respected figure among students and peers alike.