Cystic Fibrosis: Understanding Pulmonary exacerbation

The chronic infection and inflammation of cystic fibrosis (CF) in the lung causes a progressive decline of lung function resulting in symptoms like cough and sputum production. There are intermittent episodes of acute worsening of symptoms, more commonly referred to as pulmonary exacerbations....

• The standard method for lung biopsy, transbronchial lung biopsy via bronchoscopy, carries a risk of pneumothorax, which is also present in CT-guided biopsies. Cryobiopsy offers a potential advantage by reducing the likelihood of pneumothorax and providing more reliable tissue samples for diagnosis.