Intrahepatic Cholestasis of Pregnancy : An Overview & Update

Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder that occurs during pregnancy, characterized by impaired bile flow and elevated levels of bile acids in the bloodstream. The exact cause of ICP is not fully understood, but hormonal changes, genetic predisposition, and environmental...

• Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder characterized by generalized pruritus without skin lesions, elevated serum bile acids, typically developing in the second or third trimester, and resolving rapidly postpartum. Incidence varies globally, with higher rates in certain ethnic groups. Obstetricians must understand ICP management to minimize stillbirth risk.